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Updated: May 22, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
Published on: August 9, 2024
[Multiple self-healing squamous epithelioma is an inherited self-healing skin cancer condition]
Sigurd Broesby-Olsen1, Stine Krog Frandsen, Mads Thomassen
1Hudafdeling I og Allergicentret, Odense Universitetshospital, Denmark.
Abstract:
Multiple self-healing squamous epithelioma - Ferguson-Smith disease (MSSE) is an autosomal dominant inherited disease with multiple, recurrent, histologically malignant tumours that undergo spontaneous regression. The gene for MSSE has recently been identified as the transforming growth factor-beta receptor 1 (TGFBR1). Although rare, MSSE constitutes an important model of tumour-biology research. The discovery of the genetic background for MSSE paves the way for further elucidating the mechanisms involved in this peculiar self-healing cancer syndrome.
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