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Published on: August 24, 2019
Effects of an exercise program on the functional capacity of patients with chronic Chagas' heart disease, evaluated
Paloma Hargreaves Fialho1, Bernardo Rangel Tura, Andréa Silvestre de Sousa
1Serviço de Reabilitação Cardíaca, Instituto Nacional de Cardiologia, Rio de Janeiro, RJ. palomahv@hotmail.com
Insights
Regular exercise significantly improves functional capacity in patients with chronic Chagas' heart disease. This study demonstrates that a tailored exercise program can enhance aerobic capacity, offering a potential non-pharmacological intervention for managing this neglected tropical disease.
Area of Science:
- Cardiology
- Exercise Physiology
- Tropical Medicine
Background:
- Chagas' disease is a major public health concern in Latin America, impacting millions.
- Chronic Chagas' heart disease leads to heart failure and reduced quality of life.
- Limited research exists on the benefits of exercise for chronic Chagas' heart disease patients.
Purpose of the Study:
- To assess the impact of a structured exercise program on the functional capacity of individuals with chronic Chagas' heart disease.
- To investigate the efficacy of combined aerobic and resistance training.
Main Methods:
- A 6-month exercise intervention was conducted with patients attending outpatient clinics.
- The program involved 3 weekly sessions, each lasting 1 hour, combining aerobic and resistance exercises.
- Functional capacity was measured using cardiopulmonary exercise testing to determine oxygen uptake volume (VO₂).
Main Results:
- Eighteen patients completed the study, with ages ranging from 30 to 72 years.
- A statistically significant average increase in peak oxygen uptake (VO₂peak) exceeding 10% was observed (p = 0.01949).
Conclusions:
- Regular exercise, when appropriately prescribed, can significantly enhance functional capacity in patients with chronic Chagas' heart disease.
- Exercise presents a promising therapeutic strategy for improving cardiovascular health and quality of life in this population.
Introduction:
Despite all efforts to restrict its transmission, Chagas' disease remains a severe public health problem in Latin America, affecting 8-12 million individuals. Chronic Chagas' heart disease, the chief factor in the high mortality rate associated with the illness, affects more than half a million Brazilians. Its evolution may result in severe heart failure associated with loss of functional capacity and quality of life, with important social and medical/labor consequences. Many studies have shown the beneficial effect of regular exercise on cardiac patients, but few of them have focused on chronic Chagas' heart disease.
Methods:
This study evaluated the effects of an exercise program on the functional capacity of patients with chronic Chagas' disease who were treated in outpatient clinics at the Evandro Chagas Institute of Clinical Research and the National Institute of Cardiology, Rio de Janeiro, Brazil. The exercises were performed 3 times a week for 1 h (30 min of aerobic activity and 30 min of resistance exercises and extension) over 6 months in 2010. Functional capacity was evaluated by comparing the direct measurement of the O₂ uptake volume (VO₂) obtained by a cardiopulmonary exercise test before and after the program (p < 0.05).
Results:
Eighteen patients (13 females) were followed, with minimum and maximum ages of 30 and 72 years, respectively. We observed an average increase of VO(2peak) > 10% (p = 0.01949).
Conclusions:
The results suggest a statistically significant improvement in functional capacity with regular exercise of the right intensity.
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