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Published on: October 14, 2016
Epidemiology of diagnosed childhood cancer in Western Kenya
Saskia Mostert1, Festus Njuguna, Luc Kemps
1Department of Paediatric Oncology-Haematology and Doctor 2 Doctor Program, VU University Medical Centre, De Boelelaan 1117, Amsterdam, 1081 HV, The Netherlands. s.mostert@vumc.nl
Insights
Childhood cancer in Western Kenya lacks basic data. This study analyzed 436 pediatric cancer cases from 2006-2010, finding Non-Hodgkin's lymphoma most common. Improved data collection may enhance outcomes.
Area of Science:
- Pediatric Oncology
- Epidemiology
- Global Health
Background:
- Basic epidemiological data on childhood cancer in Western Kenya is scarce.
- This data gap hinders efforts to improve care and survival rates for affected children.
- Understanding local cancer demographics is crucial for targeted interventions.
Purpose of the Study:
- To provide an overview of childhood cancer patients presenting for treatment in Western Kenya.
- To establish a baseline for future epidemiological studies and cancer control programs.
- To inform evidence-based oncology strategies in the region.
Main Methods:
- Retrospective analysis of pediatric cancer cases (0-19 years) diagnosed between January 2006 and January 2010.
- Data was collected from three databases at the Moi Teaching and Referral Hospital in Eldoret, Kenya.
- Inclusion criteria focused on newly diagnosed malignancies.
Main Results:
- A total of 436 children were registered with cancer.
- The most common cancers were Non-Hodgkin's lymphoma (34%) and acute lymphoblastic leukemia (15%).
- The male to female ratio was 1.4:1, with the 6-10 year age group most represented (29%).
Conclusions:
- The pattern of childhood malignancies in Western Kenya aligns with other equatorial African countries but differs from high-income nations.
- A comprehensive cancer registration system is being established to support evidence-based oncology.
- Continued data collection and analysis are expected to improve clinical outcomes for pediatric cancer patients.
Setting:
Basic epidemiological information on childhood cancer in Western Kenya is lacking. This deficit obstructs efforts to improve the care and survival rates of children in this part of the world.
Objective:
Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya.
Design:
A retrospective analysis of childhood cancer patients presenting for treatment in Western Kenya was carried out using information from three separate databases at the Moi Teaching and Referral Hospital in Eldoret. All patients aged 0-19 years first presenting between January 2006 and January 2010 with a newly diagnosed malignancy were included.
Results:
A total of 436 children with cancer were registered during the period. There were 256 (59%) boys and 180 (41%) girls with a male/female ratio of 1.4:1. The group aged 6-10 years contained most children (29%). Median age at admission was 8 years. Non-Hodgkin's lymphoma was the most common type of cancer (34%), followed by acute lymphoblastic leukaemia (15%), Hodgkin's lymphoma (8%), nephroblastoma (8%), rhabdomyosarcoma (7%), retinoblastoma (5%) and Kaposi's sarcoma (5%). Only four (1%) children with brain tumours were documented. Ewing's sarcoma was not diagnosed.
Conclusions:
Our study provides an overview of childhood cancer patients presenting for treatment in Western Kenya. The distribution of malignancies is similar to findings from other equatorial African countries but differs markedly from studies in high-income countries. The new comprehensive cancer registration system will be continued and extended to serve as the basis for an evidence-based oncology program. Eventually this may lead to improved clinical outcomes.
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