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Identification of Virulence Markers of Mycobacterium abscessus for Intracellular Replication in Phagocytes
Published on: September 27, 2018
Draft genome sequence of Mycobacterium abscessus subsp. bolletii BD(T)
Go-Eun Choi1, Yong-Joon Cho, Won-Jung Koh
1Department of Microbiology and Research Institute for Medical Sciences, College of Medicine, Chungnam National University, Daejeon, Republic of Korea.
Mycobacterium abscessus subsp. bolletii causes significant human infections. This study presents the first whole-genome sequence of this emerging, pathogenic rapidly growing mycobacteria (RGM) species.
Area of Science:
- Microbiology
- Genomics
- Infectious Diseases
Background:
- Mycobacterium abscessus subsp. bolletii is an emerging pathogen causing human pulmonary and soft tissue infections.
- Increasing reports highlight its significance as a cause of disease.
Purpose of the Study:
- To report the first whole-genome sequence of Mycobacterium abscessus subsp. bolletii BD(T).
- To provide genomic data for understanding the pathogenicity of this emerging RGM.
Main Methods:
- Whole-genome sequencing of Mycobacterium abscessus subsp. bolletii BD(T).
Main Results:
- The first complete genome sequence of M. abscessus subsp. bolletii BD(T) has been determined.
- This provides a foundational genomic resource for the species.
Conclusions:
- The availability of the M. abscessus subsp. bolletii genome sequence is crucial for future research.
- Understanding the genomics of this pathogen will aid in developing diagnostics and treatments for RGM infections.
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