Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oxygen Requirements and Growth Patterns01:29

Oxygen Requirements and Growth Patterns

1.5K
Microorganisms exhibit diverse oxygen requirements and growth patterns driven by their metabolic strategies and environmental adaptations. Oxygen, while essential for many organisms, can also be toxic under certain conditions, shaping how microorganisms grow and survive.Oxygen Requirements of MicroorganismsMicroorganisms are classified based on their ability to use or tolerate oxygen:● Obligate aerobes like Mycobacterium tuberculosis need oxygen for energy production, as it serves as the...
1.5K
Oxygenic Photosynthesis01:26

Oxygenic Photosynthesis

808
Oxygenic photosynthesis is a fundamental process in which light energy is harnessed to drive the oxidation of water, leading to the production of molecular oxygen (O₂), adenosine triphosphate (ATP), and nicotinamide adenine dinucleotide phosphate (NADPH). This process is essential for sustaining aerobic life on Earth and is primarily carried out by cyanobacteria, algae, and plants. The core of oxygenic photosynthesis lies in the thylakoid membranes, where chlorophyll pigments facilitate...
808
Oxygen Transport in the Blood01:27

Oxygen Transport in the Blood

6.9K
Hemoglobin (Hb) is a crucial molecule in the human body, consisting of four polypeptide chains, each bound to an iron-containing heme group. This unique structure enables hemoglobin to bind to oxygen, with each molecule capable of combining with four molecules of oxygen, leading to rapid and reversible oxygen loading. When fully loaded with oxygen, it is called oxyhemoglobin, while hemoglobin that has released oxygen is called reduced hemoglobin or deoxyhemoglobin. As hemoglobin binds oxygen,...
6.9K
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen01:16

Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen

2.5K
Oxygen therapy is a pivotal aspect of medical care, particularly for patients with respiratory ailments. Two prominent oxygen-delivering systems include the Venturi mask and the transtracheal oxygen catheter.
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
2.5K
Administering Oxygen by Mask01:30

Administering Oxygen by Mask

2.6K
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
2.6K
Special considerations while measuring oxygen saturation01:19

Special considerations while measuring oxygen saturation

1.0K
Assessing respiratory rate concurrently with pulse measurement is fundamental to patient care, providing valuable insights into the patient's respiratory function. The normal breathing rate for an adult usually falls within a normal range of 12 to 20 breaths per minute. Abnormal respiratory rates can signal underlying health conditions or the need for immediate intervention.
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
1.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Lipid remodeling and circulating semaphorin 3A in diminished ovarian reserve.

Scientific reports·2026
Same author

Characterizing bone injuring in avalanche fatalities in the French Alps: preliminary insights from post-mortem CT scans.

Injury·2026
Same author

Seismic energy from small earthquakes maps fault segmentation in the Southeastern Alps.

Scientific reports·2026
Same author

Cardiovascular and peripheral factors affecting the decay of maximal oxygen uptake across the spectrum of age in humans.

European journal of applied physiology·2025
Same author

Sexual abuse or traffic accidental trauma? Analysis of a case.

La Clinica terapeutica·2025
Same author

[French practical guidelines for the diagnosis and management of IPF - 2021 update, full version].

Revue des maladies respiratoires·2022

Related Experiment Video

Updated: Feb 13, 2026

Author Spotlight: Extended Oxygen Consumption Measurement in Retinal Pigment Epithelium Using Resipher
08:09

Author Spotlight: Extended Oxygen Consumption Measurement in Retinal Pigment Epithelium Using Resipher

Published on: August 16, 2024

5.6K

On maximal oxygen consumption in hypoxic humans.

G Ferretti1

  • 1Département de Physiologie, Centre Médical Universitaire, Genève, Switzerland.

Experientia
|December 1, 1990
PubMed
Summary

Hypoxia significantly impacts maximal oxygen consumption (VO2max). Acclimatization to high altitudes does not preserve VO2max, altering circulatory, tissue, and mitochondrial oxygen transport limitations.

Area of Science:

  • Physiology
  • Altitude Medicine
  • Exercise Science

Background:

  • Maximal oxygen consumption (VO2max) is crucial for aerobic performance.
  • Hypoxia at high altitudes presents challenges to oxygen delivery and utilization.
  • Understanding VO2max limitations in hypoxia is key for athletes and researchers.

Purpose of the Study:

  • To investigate the factors limiting VO2max in acute and chronic hypoxia at 4300m.
  • To quantify the fractional limitations of O2 transport, tissue transfer, and mitochondrial utilization.
  • To examine the effect of acclimatization on VO2max and its determinants.

Main Methods:

  • Analysis of VO2max limitations in acute and chronic hypoxia.
  • Calculation of fractional limitations (FQ', Ft', Fm') for O2 transport, tissue transfer, and mitochondrial utilization.

More Related Videos

Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption
07:12

Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption

Published on: December 18, 2019

5.8K
Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans
08:10

Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans

Published on: February 23, 2019

10.3K

Related Experiment Videos

Last Updated: Feb 13, 2026

Author Spotlight: Extended Oxygen Consumption Measurement in Retinal Pigment Epithelium Using Resipher
08:09

Author Spotlight: Extended Oxygen Consumption Measurement in Retinal Pigment Epithelium Using Resipher

Published on: August 16, 2024

5.6K
Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption
07:12

Analysis of Non-Human Primate Pancreatic Islet Oxygen Consumption

Published on: December 18, 2019

5.8K
Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans
08:10

Measurement of Oxygen Consumption Rates in Intact Caenorhabditis elegans

Published on: February 23, 2019

10.3K
  • Comparison of VO2max determinants between normoxia, acute hypoxia, and chronic hypoxia.

    • Main Results:

    • In acute hypoxia, circulatory O2 transport (FQ') limits VO2max by 50%, a decrease from 70% in normoxia, due to increased blood O2 carrying capacity.
    • In chronic hypoxia, acclimatization shifts limitations: FQ'=0.45, Ft'=0.20, Fm'=0.35, linked to reduced muscle fiber size and mitochondrial density.
    • The relationship between VO2max and inspired O2 partial pressure (PIO2) follows the O2 dissociation curve in both acute and chronic hypoxia.

    Conclusions:

    • Acclimatization to chronic hypoxia does not preserve VO2max.
    • Hypoxia alters the balance of O2 transport limitations, with circulatory factors becoming less limiting in acute hypoxia.
    • Muscle adaptations during acclimatization lead to reduced reliance on circulatory O2 transport but do not maintain peak oxygen uptake.