Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Chlamydia trachomatis infection in primary unexplained infertility.

G Gorini1, F Milano, P Olliaro

  • 1Institute of Infectious Disease, IRCCS Policlinico S. Matteo, University of Pavia, Italy.

European Journal of Epidemiology
|September 1, 1990
PubMed
Summary

Chlamydia trachomatis infection is a major cause of infertility. This study found C. trachomatis in 31.8% of infertile women, highlighting the need for accurate diagnostic methods like cell culture for active infections.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the psychosocial implications of general population screening for paediatric type 1 diabetes in Europe: Protocol for a mixed-methods study.

Diabetic medicine : a journal of the British Diabetic Association·2026
Same author

Haploidentical transplantation: An optimal platform for graft manipulation and cellular therapies.

Blood reviews·2025
Same author

Design studies on electronics and data acquisition of a real time diamond spectrometer for the SPARC neutron camera.

The Review of scientific instruments·2024
Same author

Overview of the early campaign diagnostics for the SPARC tokamak (invited).

The Review of scientific instruments·2024
Same author

Development of a multi-layer high-efficiency GEM-based neutron detector for spallation sources.

Scientific reports·2024
Same author

Overview of the neutron diagnostic systems for the SPARC tokamak.

The Review of scientific instruments·2024

Area of Science:

  • Reproductive Medicine
  • Infectious Diseases
  • Microbiology

Background:

  • Chlamydia trachomatis is increasingly recognized as a cause of acute salpingitis and reproductive failure.
  • Genital C. trachomatis infections can lead to long-term reproductive health issues.

Purpose of the Study:

  • To investigate the prevalence of Chlamydia trachomatis genital infection in women with primary infertility.
  • To compare the diagnostic accuracy of different methods for detecting C. trachomatis in infertile women.

Main Methods:

  • Screening of 85 infertile women and 85 parous women (control group) for C. trachomatis.
  • Utilized cell culture, antigen detection (immunofluorescence staining), and serology (anti-chlamydial antibodies).

Main Results:

Related Experiment Videos

  • C. trachomatis was detected in 31.8% of infertile women versus 5.8% in the control group.
  • Cell culture isolation was the most reliable diagnostic method compared to immunofluorescence and serology.
  • Serology is valuable for epidemiological research but less so for diagnosing active infection.

Conclusions:

  • Chlamydia trachomatis infection is significantly more prevalent in women with primary infertility.
  • Cell culture is the preferred method for diagnosing active C. trachomatis infections.
  • Early detection and treatment are crucial to prevent reproductive failure.