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Protonated triplex DNA in E. coli cells as detected by chemical probing
P Karlovsky1, P Pecinka, M Vojtiskova
1Institute of Biophysics, Czechoslovak Academy of Sciences, Brno.
FEBS Letters
|November 12, 1990
Abstract:
The triplex structure in vitro is well established; however, no direct evidence has been available concerning its existence in the cell. Using the direct chemical probing here we show that the triplex H structure can exist in E. coli cells at acidic intracellular pH values; this structure differs in some details from that observed in vitro.