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Related Concept Videos

Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
Chronic Pancreatitis I: Introduction01:25

Chronic Pancreatitis I: Introduction

Chronic pancreatitis is a long-standing, relapsing inflammation of the pancreas, characterized by irreversible damage to the gland. It results in progressive destruction of the pancreatic parenchyma, fibrosis, and eventual loss of both exocrine and endocrine function. The disease may evolve gradually after multiple episodes of acute pancreatitis or develop independently.EtiologyChronic pancreatitis can arise from a variety of causes:Alcohol use is the leading cause, accounting for 70–80% of...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Acute Pancreatitis II: Pathophysiology01:21

Acute Pancreatitis II: Pathophysiology

The pathophysiology of acute pancreatitis centers on injury to pancreatic acinar cells, which initiates a cascade of harmful intracellular events.This injury leads to premature activation of trypsinogen to trypsin in the pancreas. Trypsin then activates other digestive enzymes, such as chymotrypsin, elastase, and phospholipase A2, which begin breaking down pancreatic tissue. The resulting autodigestion causes local inflammation, tissue swelling, hemorrhage, and fat necrosis.Injured acinar cells...
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
Pancreas01:19

Pancreas

The pancreas, an essential organ in the human body, is a pinkish-gray elongated structure located posterior to the stomach. It extends laterally from the duodenum towards the spleen and is firmly bound to the posterior wall of the abdominal cavity. The organ's surface has a lumpy, lobular texture that gives it a unique appearance.
The broad head of the pancreas lies within the loop formed by the duodenum, while its slender body reaches towards the spleen. The tail of the pancreas is short and...

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Related Experiment Video

Updated: May 22, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
10:10

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

Published on: April 17, 2026

Giant pancreatic pseudocyst.

Syed Aslam Shah1, Muhammad Tariq Abdullah, Abdul Hadi Kakar

  • 1Department of General Surgery, Pakistan Institute of Medical Sciences, Islamabad. draslamshah@gmail.com

Journal of the College of Physicians and Surgeons--Pakistan : JCPSP
|April 28, 2012
PubMed
Summary
This summary is machine-generated.

A large pancreatic pseudocyst was surgically treated in a 56-year-old man after conservative management failed. The successful cystogastrostomy highlights a rare, large-volume pseudocyst intervention.

Related Experiment Videos

Last Updated: May 22, 2026

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms
10:10

Robotic Duodenum-preserving Total Pancreatic Head Resection for Intraductal Papillary Mucinous Neoplasms

Published on: April 17, 2026

Area of Science:

  • Gastroenterology
  • Surgical Gastroenterology
  • Abdominal Surgery

Background:

  • Pancreatic pseudocysts can develop after acute pancreatitis.
  • Conservative management is often the initial approach for pseudocysts.
  • Enlarging pseudocysts may necessitate surgical intervention.

Observation:

  • A 56-year-old male presented with epigastric pain and abdominal distension.
  • The patient had a history of acute pancreatitis 6 weeks prior, leading to pseudocyst formation.
  • The pseudocyst progressively enlarged despite conservative treatment.

Findings:

  • Surgical exploration revealed a massive pancreatic pseudocyst containing approximately 4.5 liters of fluid.
  • Cystogastrostomy was performed as the surgical procedure.
  • The patient experienced an uneventful recovery post-surgery.

Implications:

  • This case represents the third-largest pancreatic pseudocyst reported in medical literature.
  • Cystogastrostomy is an effective treatment for large pancreatic pseudocysts.
  • Management of large pancreatic pseudocysts requires careful consideration of surgical options.