Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study of out-of-field dose in photon radiotherapy: A commercial treatment planning system versus measurements and Monte Carlo simulations.

Medical physics·2020
Same author

European Federation of Organisations for Medical Physics (EFOMP) policy statement 12.1: Recommendations on medical physics education and training in Europe 2014.

Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB)·2014
Same author

Experimental determination of the effective point of measurement and the displacement correction factor for cylindrical ionization chambers in a 6 MV photon beam.

Physics in medicine and biology·2012
Same author

Experimental determination of the effective point of measurement for cylindrical ionization chambers in 60Co gamma radiation.

Physics in medicine and biology·2012
Same author

The determination of beam quality correction factors: Monte Carlo simulations and measurements.

Physics in medicine and biology·2009
Same author

Development and validation of a beam model applicable to small fields.

Physics in medicine and biology·2009

Related Experiment Video

Updated: May 22, 2026

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

Development and validation of a BEAMnrc component module for a miniature multileaf collimator.

E Doerner1, G H Hartmann

  • 1Medical Radiation Physics, German Cancer Research Center-DKFZ, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. e.doerner@dkfz-heidelberg.de

Physics in Medicine and Biology
|April 28, 2012
PubMed
Summary

A new mini multileaf collimator (mMLC) component module for BEAMnrc Monte Carlo simulations accurately models the ModuLeaf, showing excellent agreement with measurements for key dosimetric parameters.

More Related Videos

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
10:42

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh

Published on: May 3, 2019

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Related Experiment Videos

Last Updated: May 22, 2026

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor
10:24

Neutron Radiography and Computed Tomography of Biological Systems at the Oak Ridge National Laboratory's High Flux Isotope Reactor

Published on: May 7, 2021

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh
10:42

Preparing an Isotopically Pure 229Th Ion Beam for Studies of 229mTh

Published on: May 3, 2019

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition
06:20

Irradiator Commissioning and Dosimetry for Assessment of LQ α and β Parameters, Radiation Dosing Schema, and in vivo Dose Deposition

Published on: March 11, 2021

Area of Science:

  • Medical Physics
  • Computational Dosimetry
  • Radiation Oncology

Background:

  • Accurate modeling of radiation therapy equipment is crucial for precise dose delivery.
  • Existing Monte Carlo simulation tools may require enhanced capabilities for novel collimator designs.

Purpose of the Study:

  • To develop and validate a new component module (CM) for the BEAMnrc Monte Carlo code, simulating the ModuLeaf miniature multileaf collimator (mMLC).
  • To assess the accuracy of the new mMLC CM in predicting dosimetric parameters for a 6 MV PRIMUS linear accelerator.

Main Methods:

  • Developed a new mMLC CM within the EGSnrc platform, leveraging the Microsoft Visual Studio environment.
  • Modeled a PRIMUS linac with the ModuLeaf mMLC.
  • Validated the CM using ray-tracing for geometric accuracy and by comparing calculated vs. measured output factors, dose profiles, penumbra, and interleaf leakage.

Main Results:

  • The new mMLC CM demonstrated excellent agreement between calculated and measured dosimetric parameters.
  • Ray-tracing confirmed the correct geometry of the simulated multileaf collimator.
  • The CM allows for higher accuracy investigation of leaf position and field edge relationships than direct measurement.

Conclusions:

  • The developed mMLC CM for BEAMnrc is a validated and useful tool for accurate Monte Carlo simulations of the ModuLeaf system.
  • This enhanced modeling capability can improve the precision of radiation treatment planning and analysis.