Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Cognitive Development During Adulthood01:30

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Perceptions of music listening for pain management: a multi-method study.

BMJ open·2025
Same author

Music to prevent deliriUm during neuroSurgerY (MUSYC): a single-centre, prospective randomised controlled trial.

BMJ open·2023
Same author

Prognostic factors for chronic post-surgical pain after lung and pleural surgery: a systematic review with meta-analysis, meta-regression and trial sequential analysis.

Anaesthesia·2023
Same author

Implementation of music in the perioperative standard care of colorectal surgery: study protocol of the IMPROVE Study.

BMJ open·2021
Same author

Music to prevent deliriUm during neuroSurgerY (MUSYC) Clinical trial: a study protocol for a randomised controlled trial.

BMJ open·2021
Same author

Delirium in neurosurgery: a systematic review and meta-analysis.

Neurosurgical review·2021
Same journal

[Journal Club].

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Effect of anticholinergic burden on cardiac functions in older patients.

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

[Communication in later life under institutional conditions : Professional perspectives on communication of ageing people with profound intellectual and multiple disabilities].

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
Same journal

Zeitschrift fur Gerontologie und Geriatrie·2026
See all related articles

Related Experiment Videos

Postoperative cognitive dysfunction in geriatric patients.

K A Hartholt1, T J M van der Cammen, M Klimek

  • 1Section of Geriatric Medicine, Department of Internal Medicine, Erasmus MC, University Medical Center Rotterdam, 3000, Rotterdam, The Netherlands.

Zeitschrift Fur Gerontologie Und Geriatrie
|April 28, 2012
PubMed
Summary
This summary is machine-generated.

Postoperative cognitive dysfunction (POCD) affects geriatric patients after surgery, with unknown causes but significant impacts. This review covers recent advances in preventing, diagnosing, and treating POCD.

Related Experiment Videos

Area of Science:

  • Anesthesiology
  • Geriatric Medicine
  • Neuroscience

Background:

  • Postoperative cognitive dysfunction (POCD) is a serious complication, particularly in elderly patients undergoing surgery.
  • Factors like hospitalization, surgical extent, and inflammation may contribute to POCD.
  • The precise etiology of POCD remains elusive despite identified risk factors.

Purpose of the Study:

  • To review recent developments in the prevention, diagnosis, and treatment of POCD.
  • To highlight the underrecognized incidence and severe consequences of POCD.
  • To discuss the potential role of anesthesia type in POCD development.

Main Methods:

  • Mini-review of current literature on POCD.
  • Analysis of risk factors, incidence, and consequences.
  • Discussion of anesthetic influences and management strategies.

Main Results:

  • POCD incidence is underestimated, potentially affecting 19-40% of patients.
  • POCD leads to delayed recovery, reduced quality of life, and increased mortality.
  • Anesthesia type's influence on POCD is under investigation.

Conclusions:

  • Early recognition and intervention are crucial for managing POCD.
  • Further research is needed to elucidate POCD etiology and optimize treatment.
  • Multifaceted approaches are required for effective POCD prevention and management.