Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Extraction: Advanced Methods00:56

Extraction: Advanced Methods

Metal ions can be separated from one another by complexation with organic ligands–the chelating agent– to form uncharged chelates. Here, the chelating agent must contain hydrophobic groups and behave as a weak acid, losing a proton to bind with the metal. Since most organic ligands used in this process are insoluble or undergo oxidation in the aqueous phase, the chelating agent is initially added to the organic phase and extracted into the aqueous phase. The metal-ligand complex is formed in...
Automatic Processing and Automatic Social Behavior01:28

Automatic Processing and Automatic Social Behavior

Automatic processing refers to the cognitive operations that occur without conscious intent or awareness, playing a fundamental role in shaping social cognition and behavior. These processes enable individuals to navigate complex social environments efficiently by relying on mental shortcuts and pre-existing knowledge structures known as schemas. One of the most influential mechanisms underlying automatic processing is priming, which subtly activates mental representations through exposure to...
Language Development01:22

Language Development

Children master language quickly and with relative ease, supported by both biological predisposition and reinforcement. B. F. Skinner (1957) proposed that language is learned through reinforcement, while Noam Chomsky (1965) argued that language acquisition mechanisms are biologically determined.
The critical period for language acquisition suggests that the ability to acquire language is at its peak early in life. As people age, this proficiency decreases. Language development begins very...
Retrieval01:12

Retrieval

Retrieval is the process of getting information out of memory storage and back into conscious awareness. This ability is essential for daily tasks like brushing hair and teeth, driving to work, and performing job duties. Retrieval occurs in three ways: recall, recognition, and relearning.
Recall involves accessing information without cues, such as during an essay test, where individuals must retrieve facts and concepts from memory unaided. Another example is remembering the name of a colleague...
Language and Cognition01:27

Language and Cognition

Language serves as a bridge between ideas and communication, influencing how individuals perceive and interact with the world. Psychologists have long debated whether language shapes thought or vice versa. This discussion gained grip with Edward Sapir and Benjamin Lee Whorf in the 1940s, who proposed that language determines thought, a concept known as linguistic determinism. They suggested that the vocabulary and structure of a language influence how its speakers think and perceive reality.
Improving Translational Accuracy02:07

Improving Translational Accuracy

Base complementarity between the three base pairs of mRNA codon and the tRNA anticodon is not a failsafe mechanism. Inaccuracies can range from a single mismatch to no correct base pairing at all. The free energy difference between the correct and nearly correct base pairs can be as small as 3 kcal/ mol. With complementarity being the only proofreading step, the estimated error frequency would be one wrong amino acid in every 100 amino acids incorporated. However, error frequencies observed in...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Prediction of cognitive performance by demographics, sleep, and brain morphometry: machine learning findings from ENIGMA-Sleep Working Group.

Research square·2026
Same author

PAD4 deletion in synovial macrophages exacerbates pathology in inflammatory arthritis.

Research square·2026
Same author

Enhancing the quality and trustworthiness of large language model-generated summaries of clinical oncology literature.

JAMIA open·2026
Same author

The interactions between sleep difficulties and clinical features in children with rare genetic syndromes: a structural equation modelling approach.

BMC pediatrics·2026
Same author

Geometric brain signatures of Alzheimer's disease progression and subtypes.

medRxiv : the preprint server for health sciences·2026
Same author

Unravelling the structure of broadband white-emitting silver nanoclusters stabilized in sulfur-doped zeolites.

Nanoscale·2026

Related Experiment Video

Updated: May 22, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

Boosting automatic event extraction from the literature using domain adaptation and coreference resolution.

Makoto Miwa1, Paul Thompson, Sophia Ananiadou

  • 1The National Centre for Text Mining (NaCTeM), UK. makoto.miwa@manchester.ac.uk

Bioinformatics (Oxford, England)
|April 28, 2012
PubMed
Summary

This study enhances biomedical event extraction (EE) by integrating coreference resolution (CR) and domain adaptation (DA) into the EventMine system. These improvements significantly boost EE performance and coverage, outperforming previous top systems.

Related Experiment Videos

Last Updated: May 22, 2026

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness
03:14

Augmenting Large Language Models via Vector Embeddings to Improve Domain-Specific Responsiveness

Published on: December 6, 2024

Area of Science:

  • Biomedical Natural Language Processing
  • Information Extraction

Background:

  • Existing biomedical event extraction (EE) systems face performance limitations due to inadequate handling of coreference in training corpora.
  • Training EE systems on single corpora restricts their overall coverage and accuracy in recognizing biomedical entities and events.

Purpose of the Study:

  • To enhance the EventMine system for improved biomedical event extraction.
  • To address limitations in coreference and corpus coverage in EE systems.

Main Methods:

  • Integrated a novel coreference resolution (CR) system, achieving high performance in resolving anaphoric references to proteins.
  • Incorporated domain adaptation (DA) methods to enable training on multiple annotated corpora, expanding EE coverage.
  • Developed methods to increase the generality and efficiency of the EventMine system.

Main Results:

  • The integrated CR system surpasses top-ranked systems in the BioNLP'11 COREF subtask.
  • The enhanced EventMine system demonstrates significant improvements in EE F-Score (0.5%-3.4%).
  • The improved EventMine outperforms leading systems from BioNLP'09 and BioNLP'11 shared tasks.

Conclusions:

  • The combination of CR and DA significantly advances biomedical event extraction capabilities.
  • The enhanced EventMine system offers improved accuracy and broader coverage for biomedical information extraction.
  • The updated EventMine system is publicly available for research use.