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Dialing down SUN1 for laminopathies
1Department of Genetics, Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Cell
|May 1, 2012
Abstract:
Laminopathies, caused by mutations in A-type nuclear lamins, encompass a range of diseases, including forms of progeria and muscular dystrophy. In this issue, Chen et al. provide evidence that elevated expression of the nuclear inner membrane protein SUN1 drives pathology in multiple laminopathies.

