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Biomarkers: an overview for oncology nurses
1Division of Cancer Prevention, National Cancer Institute, Rockville, MD 20892-7317, USA. richmone@mail.nih.gov
Seminars in Oncology Nursing
|May 1, 2012
Summary
Biomarker use in oncology integrates diverse data from genes to patient history, enhancing patient care. Advances in genomic technologies and bioinformatics offer new insights for personalized medicine and improved patient outcomes.
Area of Science:
- Oncology
- Genomics
- Bioinformatics
Background:
- Biomarkers are crucial in clinical oncology, encompassing diverse forms like genes and constitutional characteristics.
- Biomarkers serve both disease- and drug-related functions, utilizing modalities from protein expression to patient history.
Purpose of the Study:
- To overview basic principles of biomarker use in clinical oncology.
- To discuss the range of biomarker forms, functions, modalities, validation criteria, and the role of bioinformatics.
Main Methods:
- Review of published nursing and medical literature.
Main Results:
- Biomarker use aligns with nursing assessment principles, linking biological variables across organizational levels.
- Genomic technologies have significantly expanded the volume and potential insights from biomarkers.
Conclusions:
- Molecular biomarkers in patient care offer substantial benefits for nurses and patients.
- Personalized medicine, driven by post-genomic insights, promises improved patient assessment and outcomes.
- Continuous education is vital to leverage rapid technological advancements in healthcare.
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