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Related Concept Videos

Teratogenicity01:07

Teratogenicity

The ability of a drug to produce structural deformations and functional abnormalities in the developing embryo or the fetus is called teratogenicity, and the drug producing this effect is known as a teratogen. Teratogenic effects include stillbirth, miscarriage, intrauterine growth restriction, and neurocognitive delay. A teratogen may affect the embryo at different stages of development, which is important in determining the type and extent of the damage. During blastocyst formation, the early...
Fetal Circulation01:14

Fetal Circulation

Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...

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Related Experiment Video

Updated: May 22, 2026

Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
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Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators

Published on: March 21, 2018

Maternal-fetal surgery for structural malformations.

Emily A Partridge1, Alan W Flake

  • 1Center for Fetal Diagnosis and Treatment and The Children's Center for Fetal Research, Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.

Best Practice & Research. Clinical Obstetrics & Gynaecology
|May 1, 2012
PubMed
Summary
This summary is machine-generated.

Fetal intervention surgery can improve outcomes for severe congenital anomalies that threaten fetal survival or development. This surgical specialty has advanced significantly, offering new hope for specific conditions.

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Area of Science:

  • Maternal-fetal medicine
  • Pediatric surgery
  • Fetal surgery

Background:

  • Most prenatal anatomic abnormalities are surgically corrected after birth.
  • Severe malformations with poor postnatal prognosis may benefit from in-utero correction.
  • Intervention is limited to conditions hindering normal organ development.

Purpose of the Study:

  • To review the current state of maternal-fetal surgery.
  • To focus on congenital anomalies treated by prenatal intervention.
  • To identify key areas for future research in fetal surgery.

Main Methods:

  • Review of current literature and clinical applications of maternal-fetal surgery.
  • Focus on advancements in prenatal diagnosis and surgical techniques for fetal intervention.
  • Analysis of congenital anomalies amenable to in-utero surgical correction.

Main Results:

  • Significant progress in maternal-fetal surgery over the past 30 years.
  • Increased successful clinical applications of fetal intervention.
  • Identification of specific congenital anomalies benefiting from prenatal surgical correction.

Conclusions:

  • Maternal-fetal surgery is an evolving specialty offering improved outcomes for select severe fetal malformations.
  • Advances in diagnostics and surgical techniques are driving progress.
  • Further research is crucial to expand the scope and efficacy of fetal interventions.