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Updated: Feb 8, 2026
04:41
Plaquing of Herpes Simplex Viruses
Published on: November 5, 2021
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Herpes simplex epithelial and stromal keratitis: an epidemiologic update
1Department of Ophthalmology and Visual Sciences, College of Medicine, University of Illinois at Chicago, Chicago, Illinois 60612, USA.
Survey of Ophthalmology
|May 1, 2012
Summary
Herpes simplex virus (HSV) keratitis affects 1.5 million globally each year. This includes 40,000 new cases of blindness or severe vision loss from HSV eye disease annually.
Area of Science:
- Ophthalmology
- Virology
- Epidemiology
Background:
- Herpes simplex virus (HSV) causes ocular diseases like epithelial and stromal keratitis.
- HSV keratitis is a leading cause of infectious blindness globally.
- Understanding the burden of HSV keratitis is crucial for prevention and treatment.
Purpose of the Study:
- To estimate the global incidence of HSV keratitis.
- To determine the annual number of new cases of severe vision loss due to HSV keratitis.
- To discuss epidemiological factors of HSV epithelial and stromal disease.
Main Methods:
- Epidemiological analysis of global HSV keratitis incidence.
- Estimation of severe visual impairment and blindness cases.
- Review of relevant literature on HSV ocular disease.
Main Results:
- The global incidence of HSV keratitis is approximately 1.5 million cases annually.
- Around 40,000 new cases of severe monocular visual impairment or blindness occur each year.
- Significant epidemiological data regarding HSV epithelial and stromal keratitis were analyzed.
Conclusions:
- HSV keratitis represents a substantial global health burden.
- The findings highlight the urgent need for effective prevention and treatment strategies.
- Further research into HSV ocular disease epidemiology is warranted.
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