Related Experiment Video
Updated: May 22, 2026

Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
Cluster-tic syndrome as the initial manifestation of multiple sclerosis
V González-Quintanilla1, A Oterino, M Toriello
1University Hospital Marqués de Valdecilla, Santander, Cantabria, Spain.
Abstract:
We report the case of a patient diagnosed as having cluster-tic syndrome as the initial manifestation of multiple sclerosis (MS). The patient's headache bouts improved after treatment with antiepileptic drugs, steroids, and beta-interferon. Magnetic resonance imaging (MRI) scans showed a pontine demyelinating lesion involving the area of the trigeminal root inlet and main sensory nucleus. Neurophysiological studies correlated well with MRI lesions. The association between cluster-tic syndrome and MS is an exception, and the mechanism of the pain is still unknown; therefore, this case might suggest a pathophysiological relationship between the trigeminal main sensory nucleus and cluster-tic syndrome.
Related Concept Videos
Multiple Sclerosis l: Introduction
Cushing Syndrome I: Introduction
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes loosely...
Epilepsy ll: Types
Huntington Disease l: Introduction
Schizophrenia

