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Related Experiment Video

Updated: May 22, 2026

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Clinical Anthropometrics and Body Composition from 3-Dimensional Optical Imaging

Published on: June 7, 2024

Imaging and clinical measurements.

Carlos Pineda¹, Walter P Maksymowych

¹Department of Medicine, Instituto Nacional de Rehabilitacion, Mexico City, Mexico.

The American Journal of the Medical Sciences

|May 1, 2012

Summary

Assessing spondyloarthritis disease activity requires further study on optimal methods and cutoffs for biologic treatments. The Ankylosing Spondylitis Disease Activity Score and magnetic resonance imaging warrant additional investigation for improved patient care.

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Area of Science:

Rheumatology and immunology
Clinical assessment and imaging

Background:

Standardized clinical and imaging parameters exist for spondyloarthritis (SpA) monitoring.
Key questions remain regarding optimal disease activity assessment and biologic treatment eligibility thresholds.

Purpose of the Study:

To identify outstanding questions in the assessment of spondyloarthritis disease activity.
To evaluate current methods for disease activity assessment and biologic agent eligibility.
To determine the role of advanced imaging in SpA management.

Main Methods:

Working group identification of critical research questions.
Review of existing validated clinical and imaging parameters for SpA.
Analysis of disease activity scoring instruments and imaging modalities.

Main Results:

The Ankylosing Spondylitis Disease Activity Score (ASDAS) may offer advantages over the Bath Ankylosing Spondylitis Disease Activity Index (BASDAI).
A BASDAI cutoff of 4 lacks validation and requires further evaluation.
The definition of "expert opinion" for disease activity is unclear.
The utility of magnetic resonance imaging (MRI) in SpA assessment needs further investigation.

Conclusions:

Further research is needed to validate ASDAS and establish appropriate BASDAI cutoffs for SpA.
Clarification is required on expert opinion in defining SpA disease activity.
The role of MRI in longitudinal SpA follow-up warrants additional investigation.