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Updated: May 22, 2026

Development of an In Vitro Ocular Platform to Test Contact Lenses
Published on: April 6, 2016
Development of methicillin-resistant Staphylococcus aureus keratitis in a dry eye patient with a therapeutic contact
Shizuka Koh1, Naoyuki Maeda, Takeshi Soma
1Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Japan. skoh@ophthal.med.osaka-u.ac.jp
Purpose:
The aim was to report a case of methicillin-resistant Staphylococcus aureus (MRSA) keratitis possibly associated with the use of a silicone hydrogel soft contact lens in a patient with dry eye.
Methods:
This is a case report.
Results:
A 61-year-old woman who wore a silicone hydrogel lens as therapy for filamentary keratitis with severe dry eye presented with pain and redness in her left eye. She developed severe keratitis with ulceration and hypopyon. The MRSA grew in the culture, and intensive systemic and topical antibiotics resolved the corneal keratitis.
Conclusions:
The MRSA may cause infectious keratitis associated with silicone hydrogel contact lens therapy.
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