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Related Experiment Video

Updated: May 22, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

The EBMT activity survey: 1990-2010.

J R Passweg1, H Baldomero, A Gratwohl

  • 1EBMT Activity Survey Office, Department of Medicine, Division of Hematology, University Hospital Basel, Basel, Switzerland. hematology@uhbs.ch

Bone Marrow Transplantation
|May 1, 2012
PubMed
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Hematopoietic stem cell transplantation (HSCT) numbers significantly increased from 2005 to 2010, with a notable rise in unrelated donor transplants. This trend highlights the growing use and accessibility of HSCT across Europe.

Area of Science:

  • Hematology
  • Transplantation Medicine
  • Oncology

Background:

  • Hematopoietic stem cell transplantation (HSCT) is a critical therapeutic modality for various hematological malignancies and non-malignant disorders.
  • The landscape of HSCT has evolved significantly, with changes in donor sources, stem cell sources, and overall transplant volume.
  • Understanding current trends in HSCT is crucial for resource allocation, research direction, and clinical practice improvement.

Purpose of the Study:

  • To analyze the trends and patterns of hematopoietic stem cell transplantation (HSCT) in Europe based on 2010 survey data.
  • To document the volume, indications, donor types, and stem cell sources used in HSCT across European centers.
  • To assess the growth of HSCT procedures and identify key developments, particularly concerning unrelated donor transplantation.

Related Experiment Videos

Last Updated: May 22, 2026

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data
11:21

Methodology for Establishing a Community-Wide Life Laboratory for Capturing Unobtrusive and Continuous Remote Activity and Health Data

Published on: July 27, 2018

Main Methods:

  • A survey was conducted in 2010, contacting 654 centers across 48 countries.
  • Data on hematopoietic stem cell transplantation (HSCT) procedures, including patient numbers, indications, donor types, and stem cell sources, were collected from 634 reporting centers.
  • Statistical analysis was performed to identify trends and patterns in HSCT volume and characteristics compared to previous years.

Main Results:

  • A total of 33,362 HSCT procedures were reported in 2010, with 30,012 first-time transplants (41% allogeneic, 59% autologous).
  • Leukemias and lymphoid neoplasias were the primary indications for HSCT. Unrelated donors (53%) were more frequent than HLA-identical sibling donors (41%).
  • HSCT volume increased by 19% since 2005, with a consistent annual rise of approximately 1100 procedures since 2000. Unrelated donor transplantation showed a steady increase.

Conclusions:

  • The data demonstrate a significant and continuous growth in HSCT activity in Europe since 1990, with over 30,000 procedures annually by 2010.
  • The increasing reliance on unrelated donors, facilitated by donor registries, is a key trend in contemporary HSCT practice.
  • These findings underscore the expanding role and accessibility of HSCT as a treatment option for a wide range of diseases.