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Related Experiment Video

Updated: May 22, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia
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Published on: August 9, 2024

Schmorl's nodes.

Kwaku A Kyere1, Khoi D Than, Anthony C Wang

  • 1Department of Neurosurgery, University of Michigan, 1500 E. Medical Center Drive, Room 3552 Taubman Center, Ann Arbor, MI 48109-5338, USA.

European Spine Journal : Official Publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society
|May 1, 2012
PubMed
Summary
This summary is machine-generated.

Schmorl's nodes (SNs) are common vertebral lesions, often asymptomatic. While the axial load model is favored, the exact cause of painful SNs remains unclear, with varied management options available.

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Area of Science:

  • Spine imaging and pathology
  • Vertebral body disorders

Background:

  • Schmorl's nodes (SNs) involve nucleus pulposus herniation into vertebrae.
  • Most SNs are asymptomatic, but some cause pain.

Purpose of the Study:

  • To review the epidemiology, clinical presentation, pathogenesis, imaging, and management of Schmorl's nodes.

Main Methods:

  • Literature search of US National Library of Medicine and National Institutes of Health databases.

Main Results:

  • The axial load model has the most evidence for SN pathogenesis.
  • Symptomatic SNs may result from inflammation due to nucleus pulposus herniation.
  • Management ranges from conservative to surgical fusion.

Conclusions:

  • Schmorl's nodes are common and frequently asymptomatic.
  • Pathogenesis lacks consensus, and no standard treatment exists for symptomatic cases.