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Inflammatory linear verrucous epidermal nevus with genital involvement
Didem Didar Balci1, Jülide Zehra Yenin, Ebru Celik
1Department of Dermatology, Mustafa Kemal University, Hatay, Turkey. didemaltiner@yahoo.com
Skinmed
|May 2, 2012
Summary
Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare condition. Cryotherapy effectively treated itching and erosion but not papules in an 18-year-old woman.
Area of Science:
- Dermatology
- Histopathology
Background:
- Inflammatory linear verrucous epidermal nevus (ILVEN) is a rare congenital condition characterized by pruritic, verrucous papules.
- This case presents an 18-year-old woman with lifelong symptoms unresponsive to conventional therapies.
Observation:
- The patient exhibited linear, verrucous papules in the inguinal and genital areas, with intergluteal erosion.
- Histopathology revealed epidermal changes including papillomatosis and acanthosis, with dermal inflammatory infiltrate.
Findings:
- Cryotherapy provided significant relief from itching and promoted re-epithelialization of eroded lesions within two weeks.
- However, cryotherapy showed no improvement in the papular component of the epidermal nevus after four sessions.
Implications:
- Cryotherapy may be a viable treatment option for symptomatic relief in ILVEN, particularly for erosive components.
- Further research is needed to explore effective treatments for the persistent papular lesions in ILVEN.
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