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Tailored text messaging intervention for HIV adherence: a proof-of-concept study
Megan A Lewis1, Jennifer D Uhrig, Carla M Bann
1Health Communication Program, RTI International, Research Triangle Park, NC 27709-2194, USA. melewis@rti.org
Summary
Text messages tailored to individuals living with HIV (PLWH) improved medication adherence and key clinical outcomes like viral load and CD4 counts. This dynamic messaging approach shows promise for enhancing HIV management.
Area of Science:
- Digital Health
- HIV Medicine
- Public Health
Background:
- Medication adherence is crucial for managing HIV.
- Text messaging interventions offer a scalable approach to support patient adherence.
- Tailored messages may improve engagement and effectiveness.
Purpose of the Study:
- To evaluate the reception and impact of dynamically tailored medication messages via text for people living with HIV (PLWH).
- To assess the effect of this intervention on medication adherence and clinical outcomes.
Main Methods:
- A preexperimental proof-of-concept study involving 52 HIV-positive men who have sex with men (MSM).
- Participants received tailored text messages over 3 months and answered weekly adherence queries.
- Clinical outcomes (CD4 count, viral load) were tracked via medical records.
Main Results:
- Participants found the text messaging intervention acceptable and engaging.
- Significant improvements in self-reported medication adherence were observed in initially nonadherent individuals.
- Overall viral load decreased, and CD4 counts increased from baseline to follow-up.
Conclusions:
- Dynamically tailored, two-way text messaging interventions are well-received by PLWH.
- This digital health strategy can effectively enhance medication adherence.
- The intervention shows potential for improving critical clinical outcomes in HIV management.
