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Adenovirus type 21 bronchopneumonia in infants and young children

A G James, W R Lang, A Y Liang

    The Journal of Pediatrics
    |October 1, 1979
    PubMed

    Insights

    Adenovirus type 21 caused a severe bronchopneumonia epidemic in young children in 1977. Many children experienced long-term lung issues, highlighting the illness

    Area of Science:

    • Pediatrics
    • Infectious Diseases
    • Pulmonology

    Background:

    • An epidemic of bronchopneumonia occurred in Auckland, New Zealand, in 1977.
    • Adenovirus type 21 was identified as the causative agent.

    Purpose of the Study:

    • To describe the clinical presentation and outcomes of adenovirus type 21 bronchopneumonia in infants and young children.
    • To assess the long-term pulmonary sequelae.

    Main Methods:

    • Retrospective case series of 18 children diagnosed with bronchopneumonia.
    • Clinical and radiological assessment at diagnosis and 6-12 months follow-up.

    Main Results:

    • Eighteen children aged 4-44 months were affected.
    • While no deaths occurred, 13 children showed radiologic signs of residual disease at follow-up.
    • Six children had persistent clinical signs of pulmonary disease.

    Conclusions:

    • Adenovirus type 21 causes serious bronchopneumonia in young children.
    • The infection is a significant cause of chronic lung disease in this age group.
    • Long-term pulmonary sequelae are common.

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