Related Experiment Video
Updated: May 22, 2026

Control of Eating Behavior Using a Novel Feedback System
Published on: May 8, 2018
Leptin and the central control of feeding behavior
Luc Pénicaud1, Sophie Meillon, Laurent Brondel
1CNRS, UMR6265 Centre des Sciences du Goût et de l'Alimentation, F-2100 Dijon, France. Luc.Penicaud@u-bourgogne.fr
Abstract:
The discovery of leptin by Friedman and coll. in 1995 was a major step forward in our comprehensive view of energy homeostasis. Since the original paper, a tremendous amount of work has been performed in laboratories all over the world. Many recent reviews have described this work in details. In the present review, we focus on the role of leptin on food intake. It is accepted by most authors working in this field that the control of food intake can be divided in two closely-related system: the homeostatic system and the hedonic system. Leptin has been shown to act on both systems.
Related Concept Videos
Regulation of Food Intake
Diencephalon: Hypothalamus and Coordination
The hypothalamus interacts with other brain regions, including the pituitary gland, through a direct physical connection called the hypothalamic-pituitary axis. The hypothalamus receives somatic and visceral inputs and...
Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
Diencephalon: Anatomical Regions
Cell Specific Gene Expression
Regulation of Metabolism

