Related Experiment Video
Updated: Aug 19, 2026

Batch Immunostaining for Large-Scale Protein Detection in the Whole Monkey Brain
Published on: July 27, 2009
Hypercalcemia and disseminated histoplasmosis in an owl monkey
R E Weller1, G E Dagle, C A Malaga
1Battelle, Pacific Northwest Laboratories, Richland, WA.
Abstract:
An adult male owl monkey (Aotus nancymai) had hypercalcemia associated with a disseminated case of histoplasmosis (Histoplasma capsulatum var. capsulatum). Histopathologic examination of tissues at necropsy showed moderate to marked numbers of small granulomas involving multiple organs. The granulomas contained numerous round, basophilic, intracellular structures, 1-2 microns in diameter, that stained positive in Periodic acid-Schiff and Gomori's methenamine silver tests. The hypercalcemia in this case was attributed to enhance conversion of dietary vitamin D to 1,25-dihydroxycholecalciferol by the granulomas.
Related Concept Videos
Cryptococcal Meningitis
Toxoplasmosis
Amebiasis

