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[Epigenetic regulation of osteoclastogenesis by histone modification]

Yasunori Omata1, Sakae Tanaka

  • 1Department of Orthopaedic Surgery, The University of Tokyo Hospital, Japan.

Clinical Calcium
|May 3, 2012
PubMed

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The histone proteins have a flexible N-terminal tail extending out from the nucleosome. These histone tails are often subjected to post-translational modifications such as acetylation, methylation, phosphorylation, and ubiquitination. Particular combinations of these modifications form “histone codes” that influence the chromatin folding and tissue-specific gene expression.
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Epigenetic Regulation

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