Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

EPS and iPS Cells in Disease Research01:21

EPS and iPS Cells in Disease Research

Embryonic and induced pluripotent stem cells are excellent models for disease research because of their ability to self-renew and differentiate into most cell types. Somatic cells from a patient are isolated and reprogrammed into induced pluripotent stem cells or iPSCs. These iPSCs are later differentiated into the desired cell type, which mirrors the diseased cell of the patient. In this way, disease models have been created for investigating diseases such as Down syndrome, type I diabetes,...
Multipotency of Hematopoietic Stem Cells01:19

Multipotency of Hematopoietic Stem Cells

The hematopoietic stem cells or HSCs are multipotent, meaning they can differentiate and give rise to all blood and immune cells. HSCs are maintained in the quiescent stage until an external stimulus initiates their differentiation. The multipotent HSCs exist as two heterogeneous populations, long-term repopulating cells (LTRC) and short-term repopulating cells (STRC). The two HSC populations have different surface markers or receptors and are classified based on quiescence and long-term...
Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Impaired lipoprotein secretion by APOE4 leads to lysosomal and mitochondrial dysfunction in human microglia.

bioRxiv : the preprint server for biology·2026
Same author

Aberrant CD4<sup>+</sup> T cell refeeding response impairs neuro-immune crosstalk in Parkinson's disease.

bioRxiv : the preprint server for biology·2026
Same author

Scalable longitudinal imaging and transcriptomics of cells in dynamic enclosures.

bioRxiv : the preprint server for biology·2026
Same author

RUNX1 and YY1 modulate neuronal fate and energy metabolism in Alzheimer's disease.

bioRxiv : the preprint server for biology·2026
Same author

CK2 inhibition suppresses glial inflammation in models of neuroinflammation and neurodegeneration.

Nature communications·2026
Same author

DNA damage drives a unique, Alzheimer's disease-relevant senescent state in neurons.

bioRxiv : the preprint server for biology·2026

Related Experiment Video

Updated: May 22, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
11:27

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

Neural stem cells: mechanisms and modeling.

Jun Yao1, Yangling Mu, Fred H Gage

  • 1Laboratory of Genetics, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

Protein & Cell
|May 3, 2012
PubMed
Summary
This summary is machine-generated.

Adult neural stem cells in the brain aid learning, memory, and repair. Induced pluripotent stem cell technology offers new ways to study brain disorders.

More Related Videos

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery
07:43

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery

Published on: August 23, 2016

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons
11:52

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons

Published on: August 26, 2021

Related Experiment Videos

Last Updated: May 22, 2026

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain
11:27

Growing Neural Stem Cells from Conventional and Nonconventional Regions of the Adult Rodent Brain

Published on: November 18, 2013

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery
07:43

An Enzyme- and Serum-free Neural Stem Cell Culture Model for EMT Investigation Suited for Drug Discovery

Published on: August 23, 2016

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons
11:52

Establishment of an Electrophysiological Platform for Modeling ALS with Regionally-Specific Human Pluripotent Stem Cell-Derived Astrocytes and Neurons

Published on: August 26, 2021

Area of Science:

  • Neuroscience
  • Stem Cell Biology

Background:

  • Adult neural stem cells reside in specific brain niches like the dentate gyrus and subventricular zone.
  • These stem cells generate new neurons essential for cognitive functions and brain self-repair.
  • Understanding neural stem cell physiology is crucial for research into synaptic plasticity and neurological disorders.

Purpose of the Study:

  • To review research progress on adult neural stem cells.
  • To discuss the application of induced pluripotent stem cell technology in studying neuronal disorders.

Main Methods:

  • Literature review of studies on adult neural stem cells.
  • Review of research utilizing induced pluripotent stem cells for neuropathological studies.

Main Results:

  • Adult neural stem cells play vital roles in brain plasticity and repair mechanisms.
  • Induced pluripotent stem cell technology is a valuable tool for investigating the pathology and pharmacology of neurological conditions.

Conclusions:

  • Continued research into adult neural stem cells is important for understanding brain function and disease.
  • Induced pluripotent stem cell technology holds significant promise for advancing the study and treatment of neuropathological conditions.