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Related Experiment Video

Updated: May 22, 2026

Manual Isolation of Adipose-derived Stem Cells from Human Lipoaspirates
07:23

Manual Isolation of Adipose-derived Stem Cells from Human Lipoaspirates

Published on: September 26, 2013

Human collagen isolated from adipose tissue.

Beob Soo Kim1, Ji Suk Choi, Jae Dong Kim

  • 1Dept. of Bionanotechnology, Hanyang University, Ansan, Gyeonggi-do 426-791, Republic of Korea.

Biotechnology Progress
|May 3, 2012
PubMed
Summary

Human adipose tissue from liposuction is a novel source for extracting collagen. This human collagen supports stem cell adhesion and proliferation, showing potential for medical and cosmetic applications.

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Area of Science:

  • Biomaterials Science
  • Tissue Engineering
  • Biochemistry

Background:

  • Collagen is a vital vertebrate protein used in medicine and pharmaceuticals.
  • Current collagen sources are primarily animal-derived or from cadavers.
  • Human adipose tissue is an abundant, often discarded, biological resource.

Purpose of the Study:

  • To investigate human adipose tissue as a source for collagen extraction.
  • To characterize the properties of human adipose-derived collagen.
  • To evaluate the biocompatibility of this collagen for cell culture.

Main Methods:

  • Extracellular matrix (ECM) isolation from adipose tissue via physical and chemical treatments.
  • Collagen purification from ECM using pepsin digestion in acetic acid.

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Last Updated: May 22, 2026

Manual Isolation of Adipose-derived Stem Cells from Human Lipoaspirates
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Published on: September 26, 2013

An Improved Method for the Preparation of Type I Collagen From Skin
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An Improved Method for the Preparation of Type I Collagen From Skin

Published on: January 21, 2014

Innovative Adipose Tissue Fractionation for Transforming Fat into Specialized Components
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  • Characterization using spectroscopy (FTIR, CD), electrophoresis, and amino acid analysis.

    • Main Results:

    • Successfully extracted and purified human collagen from adipose tissue.
    • Characterization confirmed a typical triple helix structure and good thermal stability.
    • Adipose-derived collagen enhanced adhesion and proliferation of stem cells and fibroblasts.

    Conclusions:

    • Human adipose tissue is a viable and plentiful source for human collagen.
    • The extracted collagen possesses favorable structural and functional properties.
    • This collagen holds significant potential for applications in cosmetics, pharmaceuticals, and regenerative medicine.