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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Prescription, Nonprescription and Orphan Drugs01:02

Prescription, Nonprescription and Orphan Drugs

Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Dosage Regimen: Individualization01:24

Dosage Regimen: Individualization

Individualization in dosing regimens is the customization of medication doses for individual patients. Its necessity arises from the goal of maximizing therapeutic benefits while minimizing risks. This approach is pivotal because human responses to drugs can vary widely; what is effective for one person may be inadequate or excessive for another. Interpatient (intersubject) variability refers to differences in drug responses between individuals, while intrapatient (intrasubject) variability...
Drug Regulation01:25

Drug Regulation

Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Drug Control Governance: Regulatory Bodies and Their Impact01:03

Drug Control Governance: Regulatory Bodies and Their Impact

Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with a...
Pharmaceutical Poisoning: Potential Scenarios01:26

Pharmaceutical Poisoning: Potential Scenarios

Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...

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Related Experiment Video

Updated: May 22, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
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Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses

Published on: August 30, 2018

Prescribing indicators: what can Canada learn from European countries?

I S Sketris1, J E Fisher, E M Langille Ingram

  • 1College of Pharmacy, Dalhousie University, Halifax, Nova Scotia, Canada. ingrid.sketris@dal.ca

Journal of Population Therapeutics and Clinical Pharmacology = Journal De La Therapeutique Des Populations Et De La Pharmacologie Clinique
|May 3, 2012
PubMed
Summary

Developing Canadian prescribing indicators can improve medication use and health outcomes by enabling comparisons and identifying variations. This approach facilitates international research and learning from European practices.

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Area of Science:

  • Health Services Research
  • Pharmacoeconomics
  • Public Health Policy

Background:

  • Suboptimal drug prescribing (underuse, overuse, inappropriate use) impacts patient quality of life and health outcomes.
  • A systematic approach is needed to identify opportunities for improving prescribing practices and medication use.

Purpose of the Study:

  • Convene diverse stakeholders to discuss drug prescribing indicators.
  • Foster methods for assessing safe, appropriate, and cost-effective prescribing.
  • Increase awareness of international indicator development and application for Canadian contexts.

Main Methods:

  • Convened approximately 50 stakeholders in Halifax, Canada (June 1-2, 2009).
  • Included foundational presentations on evaluating prescribing quality.
  • Utilized breakout group discussions on case studies (antibiotic use, prescribing for seniors) followed by feedback.

Main Results:

  • European countries utilize procedures and diverse mechanisms, including financial incentives, to develop and apply prescribing indicators for quality improvement.
  • Various data sources, tools, and methods exist for evaluating drug prescribing.

Conclusions:

  • Developing Canadian prescribing indicators would allow for federal/provincial/territorial and international comparisons.
  • A standardized system would identify practice variations, highlight improvement areas in prescribing and drug use, and facilitate cross-national research.
  • Canada can learn from European countries' use of prescribing indicators.