Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Autoimmune Disorders01:29

Autoimmune Disorders

Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune system...
Psychosis: Goals of Pharmacotherapy01:26

Psychosis: Goals of Pharmacotherapy

Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation. For...
Psychosis and Antipsychotic Drugs: Overview01:28

Psychosis and Antipsychotic Drugs: Overview

The term "psychosis" refers to a spectrum of mental disorders characterized by abnormal thoughts, perceptions, and behaviors. It can manifest as mood disorders, dementia, delirium with psychotic features, substance-induced psychosis with psychotic features, brief psychotic disorder, delusional disorder, schizoaffective disorder, and schizophrenia. Among all these disorders, schizophrenia is the most common psychotic disorder, affecting 1% of the worldwide population. Psychotic symptoms in all...
Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders01:27

Psychosis: Pathophysiology of Schizophrenia and Other Psychotic Disorders

Schizophrenia is a neurodevelopmental disorder whose origins are rooted in complex genetic components. Despite our burgeoning understanding, the pathophysiology of this disorder remains incompletely deciphered.
Researchers have identified genetic factors that increase susceptibility to schizophrenia, underscoring the intricate interplay between genetics and environment in disease development. At the core of schizophrenia's pathophysiology is excessive dopaminergic neurotransmission within the...
Inflammatory Bowel Disease III: Crohn's Disease01:25

Inflammatory Bowel Disease III: Crohn's Disease

Crohn’s disease is a chronic, relapsing form of inflammatory bowel disease characterized by segmental, transmural inflammation that can affect any part of the gastrointestinal tract. Its pathogenesis arises from a combination of genetic susceptibility, environmental exposures, epithelial barrier dysfunction, and immune dysregulation. Together, these factors lead to an exaggerated immune response against components of the gut microbiome.Genetic and Environmental InfluencesMultiple genetic...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Kurt Schapira.

BMJ (Clinical research ed.)·2017
Same author

A multimethod, multi-informant, and multidimensional perspective on psychosocial adjustment in preadolescents with spina bifida.

Journal of consulting and clinical psychology·2003
Same journal

Hormone blindness in precision psychiatry.

The British journal of psychiatry : the journal of mental science·2026
Same journal

What is a clinical trial? A proposal for expanding the WHO definition of a clinical trial for use in mental health research.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Artificial intelligence evolution in medicine.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Relapse and the outcome of schizophrenia and recurrent psychosis: response to a Commentary.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Psilocybin therapy for adult females with anorexia nervosa: pilot study.

The British journal of psychiatry : the journal of mental science·2026
Same journal

Effectiveness and safety of repeat dose subcutaneous ketamine for treatment-resistant depression, and the impact of prior ketamine treatment: open label extension of the KADS study.

The British journal of psychiatry : the journal of mental science·2026
See all related articles

Related Experiment Video

Updated: May 22, 2026

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
06:19

Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

Published on: September 9, 2022

Autoimmunity in psychiatry.

Kenneth Davison

    The British Journal of Psychiatry : the Journal of Mental Science
    |May 3, 2012
    PubMed
    Summary
    This summary is machine-generated.

    Autoimmunity plays a role in psychiatric disorders by affecting brain function. Understanding these immunological effects is crucial for advancing neuropsychiatric medicine.

    More Related Videos

    Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
    09:38

    Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

    Published on: September 12, 2016

    Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis
    05:55

    Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis

    Published on: December 1, 2023

    Related Experiment Videos

    Last Updated: May 22, 2026

    Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis
    06:19

    Induction and Diverse Assessment Indicators of Experimental Autoimmune Encephalomyelitis

    Published on: September 9, 2022

    Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination
    09:38

    Determining Immune System Suppression versus CNS Protection for Pharmacological Interventions in Autoimmune Demyelination

    Published on: September 12, 2016

    Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis
    05:55

    Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis

    Published on: December 1, 2023

    Area of Science:

    • Neuroimmunology
    • Psychiatry
    • Pathogenesis of psychiatric disorders

    Background:

    • Overview of current knowledge on autoimmunity in major psychiatric disorders.
    • Emphasis on the impact of immunological factors on synaptic transmission.
    • Connection between immune system dysregulation and neuropsychiatric syndromes.

    Discussion:

    • The intricate relationship between the immune system and brain function in psychiatric conditions.
    • The role of autoantibodies and immune cells in altering neuronal signaling.
    • Implications for understanding the biological underpinnings of mental illness.

    Key Insights:

    • Autoimmunity is a significant factor in the development of psychiatric disorders.
    • Immunological mechanisms directly influence synaptic function and neurotransmission.
    • Neuropsychiatric symptoms can arise from immune-mediated processes.

    Outlook:

    • Need for clinical psychiatrists to stay updated on neuroimmunology advancements.
    • Potential for novel diagnostic and therapeutic strategies targeting immune pathways.
    • Future research directions in autoimmune psychiatry.