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Related Concept Videos

Cholecystitis01:20

Cholecystitis

Cholecystitis is inflammation of the gallbladder, most commonly caused by obstruction of the cystic duct. This blockage prevents bile from draining, leading to gallbladder distension, inflammation, and potentially serious complications. This condition may present acutely or chronically and can happen with or without gallstones.EtiologyAbout 95% of cholecystitis cases are calculous, caused by gallstones blocking the cystic duct, leading to bile accumulation and inflammation of the gallbladder...
Chronic Pancreatitis II: Pathophysiology01:21

Chronic Pancreatitis II: Pathophysiology

Chronic pancreatitis is a progressive and irreversible inflammation of the pancreas, most often caused by long-term alcohol abuse, but it can also be related to ductal obstruction, smoking, or genetic factors.Chronic pancreatitis occurs when the pancreas is repeatedly exposed to harmful agents like alcohol, smoking, ductal obstruction, or genetic predisposition. These factors lead to the release of toxic metabolites and inflammatory cytokines, sustaining chronic inflammation in the pancreatic...
Cholesterol: Significance and Regulation01:29

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...
Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Chronic Pancreatitis I: Introduction01:25

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Cushing Syndrome II: Pathophysiology

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Recurrent orbitofrontal cholesterol granuloma: a case report.

David I T Sia1, Garry Davis, Dinesh Selva

  • 1Discipline of Ophthalmology & Visual Sciences, University of Adelaide and South Australian Institute of Ophthalmology, Adelaide, Australia. daviditsia@gmail.com

Orbit (Amsterdam, Netherlands)
|May 4, 2012
PubMed
Summary
This summary is machine-generated.

Orbitofrontal cholesterol granuloma, a rare condition, typically affects middle-aged men. Recurrence after surgery is uncommon but can occur, as seen in this case report.

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Area of Science:

  • Neurosurgery
  • Ophthalmology
  • Pathology

Background:

  • Orbitofrontal cholesterol granuloma is a rare benign tumor.
  • It predominantly affects males in their 40s and 50s.
  • The lesion typically occurs in the frontal bone near the lacrimal fossa.

Observation:

  • A 77-year-old male presented with recurrent orbitofrontal cholesterol granuloma.
  • The recurrence was noted 11 years post-initial surgical intervention.
  • Subtotal curettage is presumed to be the cause of recurrence.

Findings:

  • Cholesterol granuloma recurrence after surgical management is rare.
  • Complete surgical resection is crucial for preventing recurrence.
  • Endoscopic assistance may improve lesion removal completeness.

Implications:

  • This case highlights the importance of thorough surgical technique in managing orbitofrontal cholesterol granuloma.
  • Endoscopic approaches may offer improved visualization and resection.
  • Further research into optimal surgical strategies is warranted.