Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: May 22, 2026

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension
09:33

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension

Published on: September 11, 2020

Electrical field-flow fractionation for metal nanoparticle characterization.

Wilaiwan Somchue1, Atitaya Siripinyanond, Bruce K Gale

  • 1Department of Chemistry and Center for Innovation in Chemistry, Faculty of Science, Mahidol University, Rama VI Rd., Bangkok 10400, Thailand.

Analytical Chemistry
|May 4, 2012
PubMed
Summary

Electrical field-flow fractionation (ElFFF) effectively characterizes metal nanoparticles. ElFFF separates nanoparticles by electrophoretic mobility and particle size, offering insights into their properties.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Automated Flushing System for Post-Processing in Microfluidic Device Fabrication.

Micromachines·2026
Same author

Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma.

Frontiers in oncology·2026
Same author

Correction: Efficacy of local convection enhanced delivery of chemotherapy using an intracerebral osmotic pump in a rat model of glioblastoma.

Frontiers in oncology·2026
Same author

Using inductively coupled plasma mass spectrometry for studying the association of gold nanoparticles with compounds of clinical interest.

Talanta·2026
Same author

Mechanistic insight into Pb<sup>2+</sup> sensing by gallic acid-capped gold nanoparticles via SP-ICP-MS and complementary techniques.

Analytica chimica acta·2026
Same author

Effect of Key Operating Parameters on the Retention and Separation of Ions Using Cyclical Electrical Field Flow Fractionation.

Analytical chemistry·2025

Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Nanotechnology

Background:

  • Characterizing metal nanoparticles is crucial for understanding their properties and applications.
  • Electrical field-flow fractionation (ElFFF) is a separation technique with potential for nanoparticle analysis.

Purpose of the Study:

  • To investigate the efficacy of ElFFF for characterizing metal nanoparticles.
  • To examine the influence of parameters like DC voltage and flow rate on ElFFF separation.
  • To differentiate nanoparticles based on stabilizers and particle size.

Main Methods:

  • Utilized electrical field-flow fractionation (ElFFF) with varying applied DC voltage and flow rates.
  • Investigated gold nanoparticles stabilized with citrate and tannic acid.

More Related Videos

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices
09:14

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices

Published on: December 7, 2017

Related Experiment Videos

Last Updated: May 22, 2026

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension
09:33

Asymmetrical Flow Field-Flow Fractionation for Sizing of Gold Nanoparticles in Suspension

Published on: September 11, 2020

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices
09:14

Flow-assisted Dielectrophoresis: A Low Cost Method for the Fabrication of High Performance Solution-processable Nanowire Devices

Published on: December 7, 2017

  • Analyzed nanoparticles of different sizes (10, 20, and 40 nm).

    • Main Results:

    • Applied voltage significantly impacted ElFFF separation, while flow rate optimized plate heights.
    • For fixed-size nanoparticles, separation was primarily governed by electrophoretic mobility.
    • Citrate-stabilized gold nanoparticles eluted before tannic acid-stabilized ones due to lower electrophoretic mobility.
    • ElFFF successfully separated gold nanoparticles of varying sizes (10, 20, 40 nm), with separation based on particle size.

    Conclusions:

    • ElFFF is a viable technique for metal nanoparticle characterization.
    • The study demonstrates ElFFF's ability to distinguish nanoparticles by stabilizer type and size.
    • Electrophoretic mobility and particle size are key factors influencing ElFFF separation of nanoparticles.