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Computed Tomography and Optical Imaging of Osteogenesis-angiogenesis Coupling to Assess Integration of Cranial Bone Autografts and Allografts
Published on: December 22, 2015
Evaluation of bone volume changes after sinus floor augmentation with autogenous bone grafts
M Arasawa1, Y Oda, T Kobayashi
1Division of Reconstructive Surgery for Oral and Maxillofacial Region, Department of Tissue Regeneration and Reconstruction, Course for Oral Life Science, Niigata University Graduate School of Medical and Dental Sciences, Japan.
Summary
This study developed a quantitative method to assess bone volume changes after sinus augmentation. Results show significant bone loss over time, highlighting the need for monitoring augmented bone volume.
Area of Science:
- Oral and Maxillofacial Surgery
- Biomaterials Science
- Radiology
Background:
- Sinus augmentation is a common procedure to increase bone volume in the posterior maxilla.
- Accurate volumetric assessment of augmented bone is crucial for evaluating treatment outcomes.
- Existing methods may lack objectivity or precision in quantifying bone changes.
Purpose of the Study:
- To establish an objective, quantitative method for evaluating bone volume changes after sinus augmentation.
- To assess the stability of augmented bone volume over time using computed tomography (CT).
- To analyze the rate and extent of bone resorption following sinus augmentation.
Main Methods:
- Utilized computed tomography (CT) scans from 9 patients (11 sinuses) at baseline (T0), 3 months (T1), and over 1 year (T2) post-augmentation.
- Employed a 3D digital subtraction technique to isolate and extract augmented bone volumes.
- Calculated bone volumes based on voxel numbers from the extracted 3D images.
Main Results:
- Mean augmented bone volumes were 2.46 cm³ at T1 and 1.85 cm³ at T2.
- A statistically significant mean bone volume decrease of -24.8% ± 6.1% was observed between T1 and T2.
- Bone resorption was evident in most patients, with a significant negative correlation (r=-0.64) between bone volume change and elapsed time.
Conclusions:
- The developed 3D digital subtraction method provides an objective assessment of augmented bone volume changes.
- Significant bone resorption occurs between 3 months and at least 1 year after sinus augmentation.
- Long-term monitoring is essential to evaluate the stability and success of sinus augmentation procedures.
