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Published on: September 18, 2011
[Langerhans cell histiocytosis causing cervical myelopathy].
A K Doléagbénou1, J Mukengeshay Ntalaja, S Derraz
1Service de neurochirurgie, hôpital des spécialités Rabat, CHU Ibn-Sina, Rabat, Maroc. achilledole@yahoo.fr
Neuro-Chirurgie
|May 4, 2012
Summary
Langerhans cell histiocytosis (LCH) is a rare disorder. This case highlights a rare cervical spine LCH presentation causing myelopathy, successfully treated with surgery and fusion, leading to patient recovery.
Area of Science:
- Oncology
- Neurology
- Orthopedic Surgery
Background:
- Langerhans cell histiocytosis (LCH) is a rare clonal proliferative disorder of myeloid lineage cells.
- Spinal involvement in LCH is uncommon, with cervical spine and subsequent myelopathy being exceptionally rare.
Observation:
- An 8-year-old boy presented with progressive neck pain, limited mobility, and motor weakness in all limbs.
- Imaging revealed C5 vertebral body destruction and a tumor compressing the spinal cord, indicative of atypical LCH.
Findings:
- Surgical intervention involving corporectomy and anterior cervical fusion with autologous iliac bone was performed.
- Post-operative pathological examination confirmed Langerhans cell histiocytosis (LCH).
Implications:
- This case underscores the importance of considering LCH in the differential diagnosis of pediatric cervical myelopathy.
- Prompt surgical management for neurological deficits in spinal LCH can lead to significant functional recovery.
