Related Experiment Videos
Hamman-Rich syndrome revisited
J Olson1, T V Colby, C G Elliott
1Department of Pathology, Case Western Reserve University, Cleveland, Ohio.
Mayo Clinic Proceedings
|December 1, 1990
Summary
Hamman-Rich syndrome, also known as acute interstitial pneumonia, presents with organizing diffuse alveolar damage. Survival rates are similar to adult respiratory distress syndrome.
Area of Science:
- Pulmonology
- Pathology
Background:
- Hamman-Rich syndrome is a severe lung disease.
- Distinguishing it from chronic interstitial pneumonias is crucial for accurate diagnosis and treatment.
Purpose of the Study:
- To review cases of Hamman-Rich syndrome.
- To highlight its clinical and pathologic features using the term acute interstitial pneumonia.
- To compare survival rates with adult respiratory distress syndrome.
Main Methods:
- Retrospective review of 29 Hamman-Rich syndrome cases.
- Analysis of clinical presentation, histopathology, and patient outcomes.
Main Results:
- 12 out of 29 patients survived, often with prolonged hospitalization.
- Histologic findings included organizing diffuse alveolar damage.
- Extensive fibroblastic distortion was observed in some patients, including survivors.
- Survival rates were comparable to those seen in adult respiratory distress syndrome.
Conclusions:
- Acute interstitial pneumonia is a useful term for Hamman-Rich syndrome.
- The condition involves organizing diffuse alveolar damage and potential fibroblastic changes.
- Prognosis is similar to adult respiratory distress syndrome.