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Syphilitic uveitis: report of 3 cases
Shin Wei Pan1, Nor Sharina Yusof, Wan Hazabbah Wan Hitam
1Department of Ophthalmology, School of Medical Sciences, Health Campus Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
International Journal of Ophthalmology
|May 4, 2012
Summary
Syphilitic uveitis, an ocular manifestation of syphilis, can cause vision loss but often improves with penicillin treatment. Early diagnosis and treatment are key for better visual outcomes in patients with syphilis.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Immunology
Background:
- Syphilitic uveitis is a rare but serious ocular manifestation of syphilis.
- Early diagnosis and treatment are crucial for preventing vision loss.
Observation:
- A case series of three patients with syphilitic uveitis managed at Hospital USM.
- Patients presented with progressive vision blurring, ocular pain, and fever.
- Clinical findings included anterior uveitis, vitritis, papillitis, and exudative retinal detachment.
Findings:
- All patients were diagnosed with uveitis secondary to syphilis and treated with penicillin and doxycycline.
- Two patients showed significant visual improvement after treatment.
- One patient with a worse outcome was co-infected with HIV.
Implications:
- Syphilitic uveitis can present with non-granulomatous inflammation and exudative retinal detachment.
- Prompt treatment leads to generally good visual outcomes, though improvement may be slow.
- Ocular syphilis should be considered in patients with unexplained uveitis, especially those with a history of sexual promiscuity.
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