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Updated: May 22, 2026
Intravitreal Injection and Quantitation of Infection Parameters in a Mouse Model of Bacterial Endophthalmitis
Published on: February 6, 2021
Laboratory diagnosis of infectious endophthalmitis
Wen-Jiang Ma1, Hong Zhang, Shao-Zhen Zhao
1Eye Centre, Tianjin Medical University, Tianjin 300070, China.
Aim:
To analyze the lab diagnosis and etiology of infectious endophthalmitis.
Methods:
The medical and microbial records of 36 patients diagnosed with infectious endophthalmitis and 8 patients diagnosed with intraocular lens (IOL)-related inflammation between Nov. 1999 and Dec. 2009 were retrospectively reviewed for lab diagnosis and etiology.
Results:
The inflammatory cell counts in all aqueous humor specimens from infectious endophthalmitis patients were more than in all aqueous humor specimens from patients with IOL-related inflammation. Sixteen of the 36 aqueous humor samples (44.4%) and 11 of the 24 vitreous humor samples (45.8%) from infectious endophthalmitis patients showed positive results in smears; while 17 aqueous humor samples (47.2%) and 15 vitreous humor samples (62.5%) from infectious endophthalmitis patients showed positive results in culture.
Conclusion:
The inflammatory cell count may be an important index for infectious endophthalmitis; while, smears can show etiological information earlier.
