Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Applying Artificial Intelligence and machine learning in precision nutrition.

Nature communications·2026
Same author

Exploring the needs of technical developers and stakeholders in point-of-care technology development: a qualitative study.

BMJ open·2026
Same author

Integrated triplex LFIA platform for decentralized molecular subtyping of breast cancer.

RSC advances·2026
Same author

From Spreadsheet To Prediction Tool: A Practical Artificial Intelligence Guide For Urologists.

Cureus·2026
Same author

Saliva as a Matrix for Primary Care: Feasibility and Scoping of Its Use for Assessment of Nutrition and Inflammation.

Advances in nutrition (Bethesda, Md.)·2026
Same author

Artificial Intelligence-Based Diagnosis of Kaposi Sarcoma Using Digital Photographs in Dark-Skinned Patients in Uganda.

JCO global oncology·2026

Related Experiment Video

Updated: May 22, 2026

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
07:14

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging

Published on: April 11, 2025

Gel-based optical waveguides with live cell encapsulation and integrated microfluidics.

Aadhar Jain1, Allen H J Yang, David Erickson

  • 1Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, New York 14853, USA.

Optics Letters
|May 5, 2012
PubMed
Summary

Researchers created a biocompatible optical device using agarose hydrogel to encapsulate cells within an optical waveguide. This novel optofluidic system enhances light-cell interaction for advanced biological studies.

More Related Videos

Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip
14:09

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip

Published on: November 16, 2019

Related Experiment Videos

Last Updated: May 22, 2026

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging
07:14

Microfabrication of Implantable Optics Integrated in a Microstructured Imaging Window for Advanced In Vivo Imaging

Published on: April 11, 2025

Lensless Fluorescent Microscopy on a Chip
11:23

Lensless Fluorescent Microscopy on a Chip

Published on: August 17, 2011

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip
14:09

High-Throughput Total Internal Reflection Fluorescence and Direct Stochastic Optical Reconstruction Microscopy Using a Photonic Chip

Published on: November 16, 2019

Area of Science:

  • Biomedical Engineering
  • Optofluidics
  • Materials Science

Background:

  • Optical waveguides are crucial for light manipulation in various applications.
  • Encapsulating biological samples within waveguides can improve light-matter interactions.
  • Existing methods may lack biocompatibility or seamless integration.

Purpose of the Study:

  • To develop a biocompatible microscale optical device for cell encapsulation within an optical waveguide.
  • To enhance direct optical mode interaction with cells, surpassing evanescent field limitations.
  • To create an integrated optofluidic system entirely from agarose hydrogel.

Main Methods:

  • Fabrication of a microscale optical waveguide using agarose hydrogel.
  • Encapsulation of cells within the agarose hydrogel waveguide.
  • Characterization of the optical properties of the fabricated waveguide.
  • Integration of a microfluidic channel over the optical waveguide structure.

Main Results:

  • Demonstration of a functional biocompatible optical waveguide capable of cell encapsulation.
  • Confirmation of enhanced light-biology interaction via direct optical mode engagement.
  • Successful development of an integrated optofluidic system fabricated solely from agarose gel.

Conclusions:

  • The developed agarose-based optofluidic system offers a promising platform for cell-based optical studies.
  • This approach facilitates improved light-cell interaction, enabling new biological insights.
  • The all-agarose fabrication method highlights the potential of hydrogels in integrated optofluidic devices.