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Updated: May 22, 2026

NMR 15N Relaxation Experiments for the Investigation of Picosecond to Nanoseconds Structural Dynamics of Proteins
Published on: November 1, 2024
Recent progress in NMR spectroscopy: toward the study of intrinsically disordered proteins of increasing size and
Isabella C Felli1, Roberta Pierattelli
1CERM and Department of Chemistry Ugo Schiff, University of Florence, Sesto Fiorentino, Italy. felli@cerm.unifi.it
Abstract:
Thanks to recent fast progress, NMR is now in a strategic position to provide unique atomic resolution information on a variety of different biological macromolecules in different conditions (solution, solid state, in-cell). We would like here to present recent developments that enable to focus on intrinsically disordered proteins (IDPs) or intrinsically disordered regions (IDRs) of proteins of increasing size and complexity. They have attracted the attention of the scientific community challenging well accepted ideas and concepts and demanding an expansion of the structure function paradigm.
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