Contraceptive efficacy of solanum xanthocarpum berry in male rats

Oral feeding of 50% EtOH of Solanum xanthocarpum berry to male rats at the dose of 0.5 gm/kg body weight caused arrest of spermotagenesis. The number of spermatocytes (primary and secondary) and spermatids were significantly reduced (P<0.05 to 0.001). The total number of immature and mature leydig cells were significantly decreased (P<0.001), whereas degenerating cells were significantly increased (P<0.001). The decreased testicular cell population reflects antispermatogenic nature of Solanium xanthocarpum berry extract.