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Pharmacological studies of araucaria bidwilli hook
S Dhanasekaran1, S Ravishankar, K S Devi
1Department of Pharmacology, J.S.S. College of Pharmacy, Udhagamandalam - 643 001, India .
Abstract:
Leaf and oleoresin fractions of both alcoholic and petroleum ether extracts of Araucaria bidwillii exhibited significant prolongation of pentobarbitones sleeping time at a dose of 300 and 100 mg/kg body weight respectively in mice. This effect is more pronounced for oleoresin than the leaf extracts. Further, the two extracts seem to possess analgesic effect comparable to aspirin by writing method. The analgesic activity is found to be higher in oleoresin than the leaf extracts. Both the extracts are found to show high anti inflammatory activity comparable to phenylbutzaone by cotton pellet granuloma method.
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