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Related Concept Videos

Therapeutic Drug Monitoring: Overview and Classification01:16

Therapeutic Drug Monitoring: Overview and Classification

Therapeutic Drug Monitoring (TDM) is a clinical practice that measures specific drug levels in a patient's blood at designated intervals to ensure the drug concentration stays within a therapeutic range. This monitoring is crucial for optimizing individual dosage regimens, enhancing therapeutic efficacy, and minimizing drug-related toxicity. TDM is vital for drugs with narrow therapeutic windows, significant variability in pharmacokinetics, and a clear correlation between plasma levels and...
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Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
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Chemotherapy-Induced Nausea and Vomiting: Neurokinin-1 Receptor Antagonists

Neurokinin 1 (NK1) receptors are distributed across the GI tract, vagal afferents, and key CNS regions including the central vomiting center and chemoreceptor trigger zone (CTZ) Chemotherapy agents stimulate enterochromaffin cells in the gastrointestinal (GI) tract to release large amounts of substance P (SP). SP is a neuropeptide released by specific sensory nerves in response to many different stressors, including those in the GI mucosa affected by chemotherapy.  SP binds and activates these...
Drug Delivery: Parenteral Route01:29

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Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists01:29

Chemotherapy-Induced Nausea and Vomiting: Dopamine Receptor Antagonists

Dopamine receptor antagonists, also known as antipsychotic agents, are critical in managing chemotherapy-induced vomiting. These antiemetic agents block dopamine receptors in the chemoreceptor trigger zone (CTZ), inhibiting signal transmission to the vomiting center. Antipsychotic agents encompass phenothiazines (PTZ), butyrophenones, benzamides, and thienobenzodiazepines (Zyprexa), which are utilized for their antiemetic and sedative properties.
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Related Experiment Video

Updated: May 22, 2026

Quantitative Structure-Activity Relationship, Activity Prediction, and Molecular Dynamics of Non-nucleotide Reverse Transcriptase Inhibitors
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Single drug therapy in netraroga.

M B Gayathri1, M A Kareem, Sarneswar

  • 1Department of salakyatantra, Govt Ayurvedic medical college, Bangalore - 560 009.

Ancient Science of Life
|May 5, 2012
PubMed
Summary

Ayurvedic compound drugs face challenges with standardization and cost. This study identifies 41 single plant drugs from classical texts for treating eye diseases (Netrarogas), aiming to improve Ayurvedic medicine reliability.

Area of Science:

  • Ayurvedic Medicine
  • Pharmacognosy
  • Ophthalmology

Background:

  • Compound Ayurvedic drugs face issues with availability, standardization, cost, and ingredient identification.
  • Classical Ayurvedic texts emphasize single plant drug formulations for therapeutic efficacy.

Purpose of the Study:

  • To compile and botanically identify single plant drugs used in classical Ayurvedic texts for treating eye diseases (Netrarogas).
  • To provide a standardized reference for these single plant drugs to enhance the reliability of Ayurvedic treatments.

Main Methods:

  • Systematic review of 7 classical Ayurvedic texts.
  • Compilation of single plant drugs mentioned for Netrarogas.
  • Botanical identification through nomenclature correlation studies.

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  • Analysis of drug properties, preparation, and administration.
  • Main Results:

    • Identified 41 distinct single plant drugs used in 80 preparations for 9 specific symptoms (lakshanas) and 29 eye diseases (roga).
    • Established botanical identities for these drugs based on century-old nomenclature studies.
    • Arranged drugs alphabetically with detailed information on botanical names, habit, indications, parts used, preparation, administration, and references.

    Conclusions:

    • Reemphasizing single plant drug formulations in Ayurveda can address challenges associated with compound drugs.
    • This study provides a foundational, botanically identified list of single drugs for treating eye conditions in Ayurveda.
    • Standardized botanical identification is crucial for the reliable and effective use of Ayurvedic medicines.