Related Experiment Video
Updated: May 22, 2026

Fixation and Operational Method for Abdominal Massage in T2DM Mice
Published on: March 7, 2025
Hypoglycaemic action of momordica charantia in normal and diabetic mice
S Kavimani1, R Ilango, M Gupta
1Periyar college of Pharmacy, Trichy-21, Tamil Nadu, India.
Abstract:
the hypoglycemic effect of the ethanolic extract of Momordica charantia (cucurbitaceae) was investigated in both normal and streptozotocin - induced diabetic mice. The ethanolic extract of Unriped fruits of M. charantia (800mg/kg) reduced the blood glucose of normal mice from 172 ±3 to 136 ± 5 mg/100ml 4 hours after intrapertitoneal administration (P<0.001), and also significantly lowered the blood glucose of streptoxotocin induced diabetic mice from 686± 60 to 407± 35 mg/100ml under similar conditions (p<0.01). The possible mechanism of hypoglycemic action of M.Charantia is due to the increased glucose uptake in liver cells because it markedly lowers the blood glucose levels in streptozotocin induced diabetic mice.
Related Concept Videos
Diabetes Mellitus: Type 2 and Gestational
Hypoglycemia and Glucagon
Hyperglycemia
Hypoglycemia
Hormones Regulating Blood Glucose
In addition to accelerating glucose uptake and utilization, insulin has...
Oral Hypoglycemic Agents: α-Glucosidase Inhibitors
Acarbose and miglitol are typically...

