Standardisation of civanar amritam

Area of Science:

• Pharmacognosy
• Analytical Chemistry
• Traditional Medicine

Background:

• Civanar amirtam is a Siddha herbo-mineral formulation used for rheumatism, bronchial asthma, tuberculosis, and leprosy.
• The preparation consists of nine ingredients: four inorganic and five plant-derived drugs.
• Standardization is crucial for ensuring the quality and efficacy of traditional medicines.

Purpose of the Study:

• To chemically analyze Civanar amirtam to identify and quantify its constituent ingredients.
• To establish dependable quality control standards for the Civanar amirtam formulation.
• To validate the presence of both inorganic and plant-derived components.

Main Methods:

• Physico-chemical analysis of the formulation.
• Thin-Layer Chromatography (TLC) for identifying chemical constituents in plant drugs.
• Comparison of TLC profiles with authentic chemical standards.
• Quantification of inorganic ions present in the formulation.

Main Results:

• Successful identification of various chemical constituents in the plant drugs using TLC.
• Establishment of physico-chemical parameters for the formulation.
• Quantification of inorganic ions confirmed their presence.
• The analytical results confirmed the presence of all nine ingredients in Civanar amirtam.

Conclusions:

• The developed analytical methods and parameters are suitable for establishing quality standards for Civanar amirtam.
• This study provides a scientific basis for the quality control of this traditional Siddha medicine.
• The findings support the reliable use of Civanar amirtam in clinical practice for its indicated conditions.