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Standardisation of civanar amritam.

A Saraswathy1, M G Rani

  • 1Drug standardistation research Unit (Siddha), Captain Srinivasa Murti Drug Research Institute for Ayurveda, Arumbakkam, Madras - 600 106, India.

Ancient Science of Life
|May 5, 2012
PubMed
Summary

This study chemically analyzed Civanar amirtam, a traditional Siddha medicine. Analytical methods confirmed the presence of all nine ingredients, establishing quality control standards for this herbo-mineral formulation.

Area of Science:

  • Pharmacognosy
  • Analytical Chemistry
  • Traditional Medicine

Background:

  • Civanar amirtam is a Siddha herbo-mineral formulation used for rheumatism, bronchial asthma, tuberculosis, and leprosy.
  • The preparation consists of nine ingredients: four inorganic and five plant-derived drugs.
  • Standardization is crucial for ensuring the quality and efficacy of traditional medicines.

Purpose of the Study:

  • To chemically analyze Civanar amirtam to identify and quantify its constituent ingredients.
  • To establish dependable quality control standards for the Civanar amirtam formulation.
  • To validate the presence of both inorganic and plant-derived components.

Main Methods:

  • Physico-chemical analysis of the formulation.
  • Thin-Layer Chromatography (TLC) for identifying chemical constituents in plant drugs.

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  • Comparison of TLC profiles with authentic chemical standards.
  • Quantification of inorganic ions present in the formulation.
  • Main Results:

    • Successful identification of various chemical constituents in the plant drugs using TLC.
    • Establishment of physico-chemical parameters for the formulation.
    • Quantification of inorganic ions confirmed their presence.
    • The analytical results confirmed the presence of all nine ingredients in Civanar amirtam.

    Conclusions:

    • The developed analytical methods and parameters are suitable for establishing quality standards for Civanar amirtam.
    • This study provides a scientific basis for the quality control of this traditional Siddha medicine.
    • The findings support the reliable use of Civanar amirtam in clinical practice for its indicated conditions.