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Accelerated stability studies of a polyherbal preparation (eazmov(r)) capsule
S K Chauhan1, A Tyagi, B Singh
1R&D centre, Indian herbs, Post Box No 5, Saharanpur (UP), India.
Ancient Science of Life
|May 5, 2012
Summary
Eazmov capsule demonstrated excellent stability under accelerated conditions, maintaining key characteristics and active ingredients. This suggests a shelf-life exceeding three years at room temperature.
Area of Science:
- Pharmacology
- Pharmaceutical Sciences
- Herbal Medicine
Background:
- Herbal formulations require rigorous stability testing to ensure efficacy and safety.
- Understanding the shelf-life of Eazmov capsule is crucial for its therapeutic application.
Purpose of the Study:
- To assess the stability of Eazmov capsule under accelerated storage conditions.
- To determine the impact of elevated temperature and humidity on Eazmov capsule's quality.
Main Methods:
- Eazmov capsule samples were subjected to accelerated conditions (45°C/75% RH and 40°C/75% RH).
- Periodic analysis included organoleptic characteristics, active ingredient assay, and DPTLC fingerprinting with peak area analysis over six months.
Main Results:
- Eazmov capsule exhibited stable organoleptic characteristics and consistent DPTLC fingerprints throughout the study.
- Quantifiable components remained within 90% of their initial amounts, indicating minimal degradation.
Conclusions:
- Eazmov capsule demonstrates significant stability under accelerated conditions.
- The study supports a projected shelf-life of over three years for Eazmov capsule at room temperature, ensuring product integrity.
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