Related Experiment Video
Updated: May 22, 2026
05:19
Choice and No-Choice Bioassays to Study the Pupation Preference and Emergence Success of Ectropis grisescens
Published on: October 30, 2018
Experimental studies on euphorbia prostata w. Ait
1Lecturer in Ayurvedic Medicine, Kasturba Medical College, Manipal, Karnataka.
Ancient Science of Life
|May 5, 2012
Summary
The water-soluble fraction of a drug used for bronchial asthma showed significant cardiac depressant effects on frog hearts. It also demonstrated potent hypotensive and respiratory depressant actions in dogs.
Area of Science:
- Pharmacology
- Cardiovascular Research
- Respiratory Physiology
Background:
- The water-soluble fraction of a total alcoholic extract is investigated.
- Previous use in treating bronchial asthma is noted.
- The need to understand its effects on cardiovascular and respiratory systems is established.
Purpose of the Study:
- To experimentally screen the action of the water-soluble fraction on cardiovascular and respiratory systems.
- To evaluate its cardiac effects on isolated and in situ frog hearts.
- To assess its impact on dog blood pressure and respiration.
Main Methods:
- Experiments were conducted on isolated frog hearts.
- Experiments were performed on frog hearts in situ.
- Cardiovascular and respiratory effects were studied in dogs.
Main Results:
- The drug fraction exhibited cardiac depressant action on both isolated and in situ frog hearts.
- A potent hypotensive effect was observed in dogs.
- Respiratory depressant action was noted at high doses in dogs.
Conclusions:
- The water-soluble fraction possesses significant cardiac depressant properties.
- The fraction demonstrates notable hypotensive and respiratory depressant activities.
- Further research into its pharmacological profile is warranted.
