Antiurolithiatic activity of coleus Aromaticus Benth. In Rats

Water extract of the leaves of Coleus aromaticus  Benth. Was tested for its antiurolithiatic activity against calcium oxalate stones in male albino rats. Calcium oxalate stones were induced by feeding 3% w/w sodium oxalate along with normal feed. The water extract of coleus aromaticus (0.5 g/kg and 1.0 g/kg, once, orally for 30 days) was found to be effective in reducing deposition of calcium oxalate. Hence, it is suggested, coleus aromaticus leaves may be effective in the therapy of calcium oxalate stone formation in kidney and urinary tract.