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Effect of root extract of Aegle marmelos on dermal wound healing in rats
1Department of Pharmacology, Periyar college of Pharmaceutical sciences for girls, Sathanoor Main Road K.K. Nagar Post, Tiruchirappalli - 620 021, India.
Abstract:
The wound healing effect of methanolic extract of the root of aegle marmelos was evaluated in the form of an ointment with two different concentrations (5% and 10% w/w in simple ointment base) in excision wound model and incision wound model in rats. In both the concentrations, the extract ointment produced a significant response in both the wound types tested, as evidenced by its wound contracting ability, wound closure time and increase in the tensile strength. The results were also comparable to those of a standard drug nitrofurazone.