Hypolipidemic Efficacy of Achyranthes aspera on Lipid Profile in Sesame oil fed Rats

The present study was designed to evaluate the antihyperlipidemic effect of aqueous extract of Achyranthes aspera a in experimental rats fed with diet containing sesame oil. Hyperlipidemia and the effect of Achyranthes aspera in experimental rats were studied by assessing parameters such as cholesterol, phospholipids, freefattyacids and triglycerides in serum, liver, and heart and kidney tissues. The levels of HDL, LDL, VLDL and atherogenic index were assessed. Hyperlipidemia in experimental rats were evidenced by a significant enhancement in the levels of cholesterol phospholipids, freefattyacids and triglycerides in serum, liver heart and kidney tissues by atherogenic diet feeding. A significant fall in HDL in both Anjali and Idhayam oil treated groups were observed in serum. These values retrieved towards normalcy in Achyranthes aspera treated groups. This study unveiled the antihyperlipidemic activity of Achyranthes aspera.